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Description from hodgdonpowders.com:
H110 is the spherical powder that screams “no wimps, please!”, delivering top velocities with great accuracy in 44 Magnum, 454 Casull, 475 Linebaugh and the 460 and 500 S&W magnums. Silhouette shooters claim it is the most accurate 44 powder they have ever used.
In addition, H110 is “the” choice for 410-bore shotgun, especially among top competitive skeet and sporting clays shooters. It handles all 2-1/2-inch, ½-oz. loads, as well as all 11/16-oz. loads for the 3-inch version.